Treatment of Pemphigus Vulgaris and Pemphigus Foliaceus With Mycophenolate Mofetil
نویسندگان
چکیده
منابع مشابه
Treatment of pemphigus vulgaris and pemphigus foliaceus with mycophenolate mofetil.
BACKGROUND Mycophenolate mofetil is increasingly being used as a corticosteroid-sparing agent in immunosuppressive regimens. OBJECTIVE To elucidate the effectiveness of mycophenolate as adjuvant therapy in the treatment of both pemphigus vulgaris and pemphigus foliaceus. DESIGN Historical prospective study. SETTING University hospital. PATIENTS The study included 42 consecutive patients...
متن کاملMycophenolate mofetil and enteric-coated mycophenolate sodium in the treatment of pemphigus vulgaris and pemphigus foliaceus.
UNLABELLED What is known and objective: Pemphigus is a severe, potentially life-threatening autoimmune blistering disease. The use of corticosteroids has dramatically improved the prognosis and changed its course. However, current morbidity of pemphigus is largely iatrogenic, caused by side effects of the long-term, high-dose corticosteroid therapy that is necessary to sustain disease control. ...
متن کاملPemphigus Vulgaris and Pemphigus Foliaceus
The word “pemphigus” is derived from the Greek term "pemphix” meaning bubble or blister. Pemphigus is a group of autoimmune diseases (see Table 4) characterized by intra-epithelial blistering, resulting in superficial vesicles or bullae that easily rupture, resulting in ulceration of mucosal and/or cutaneous sites. Although rare, pemphigus causes significant morbidity and potential mortality fo...
متن کاملSuccessful treatment of major pemphigus vulgaris relapse with mycophenolate mofetil and high-potent topical corticosteroid
Background: Pemphigus vulgaris (PV) is an autoimmune bullous disorder that is fatal if left untreated. High dose systemic corticosteroids are the basis of therapy. The addition of immunosuppressive agents has improved the disease outcome and reduced the required corticosteroid dose and related toxicity. Mycophenolate mofetil is increasingly used as a steroid-sparing agent in immunotherapy of PV...
متن کاملRefractory pemphigus vulgaris treated with rituximab and mycophenolate mofetil*
The main treatment for pemphigus vulgaris are systemic corticosteroids and immunosuppressive agents, but due to adverse reactions and therapeutic failure, new drugs such as rituximab and mycophenolate mofetil have been used. In this case report are described two cases of severe pemphigus vulgaris refractory to various treatments, with resolution after use of rituximab and mycophenolate mofetil,...
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ژورنال
عنوان ژورنال: Archives of Dermatology
سال: 2003
ISSN: 0003-987X
DOI: 10.1001/archderm.139.6.739